Publications
2026
Fofana I., Dali B., Kone M., Sujová K., Megnassan E., Miertuš S., Frecer V.: In Silico Optimization of Inhibitors of the 3-Chymotrypsin-like Protease of SARS-CoV-2. Life 16(1), 1-30 (2026). doi: 10.3390/life16010006
Klacsová M., Sebök-Nagy K., Páli T., Chovancová M., Almásy L., Uhríková D.: Microalgae-derived vesicles as potential carriers for therapeutic biomacromolecules. Journal of drug delivery science and technology 117, art. no. 107985 (2026). doi: 10.1016/j.jddst.2026.107985.
Ivoševič deNardis N., Mišic Radic T., Klacsová M., Uhríková D., Frkanec R., Zemla J., Lekka M., Lukeš M., Prášil O., Sebők Nagy K., Páli T., Lisac K., Chovancová M., Ojdanic K., Horvat L., Peharec Štefanic P., Smokrovic K., Maltar Strmečki N., Pavlovic Saftic D., Piantanida I., Matijevic Glavan T.: Biophysical and structural characterization of biocompatible microalgae-derived vesicles as sustainable drug delivery platforms. Algal Research 98, art. no. 104852 (2026). doi: 10.1016/j.algal.2026.104852
Šišovský P., Gejgusova N., Fazekaš T., Klimas J., Štěrba J.: Molecular preselection of pediatric patients with solid tumors treated with tyrosine kinase inhibitors. Future Oncology 22(4), 491-506 (2026) doi: 10.1080/14796694.2026.2621651
Stanko P., Mačeková Z., Žufková V., Snopková M., Klimas J., Fazekaš T.: Blood pressure monitors in screening of atrial fibrillation by community pharmacists: Data from a nationwide awareness campaign. Bratislava medical journal 127(7) 3023-3033 (2026). doi: 10.1007/s44411-026-00692-1
Majsniarová Z., Mináriková D., Minárik P., Fazekaš T., Sremaňaková J.: Pharmacist-Led Interventions for Colorectal Cancer Prevention: A Systematic Review. Current Oncology 33(3), art. no. 177 (2026). doi: 10.3390/curroncol33030177
Warda R., Fazekaš T., Molitorisová M., Purnhagen K.: The Role of the Public and Private Sectors in the EU Hybrid Safety Governance of Food Supplements – A Study on the Example of Quality Issues Notified in the RASFF. Journal of consumer policy 49(12), 1-20 (2026). doi: 10.1007/s10603-026-09616-6
Mačeková Z., Hudáková N., Fazekaš T., Snopková M., Dragašek J., Žufková V., Klimas J.: Risk of mild cognitive impairment and its relation to anticholinergics revealed within screening in a community pharmacy. Bratislava medical journal 127(1) 301-310 (2026). doi: 10.1007/s44411-025-00422-z
2025
Fazekaš T., Kováčik L., Rad M.M., Barrios X.G., Iftimie S.M., Camps J., Paul Hrabovská A.: Serum butyrylcholinesterase activity as a predictor of severity and mortality in COVID-19 patients. Scientific reports 15(1), art. no. 23437 (2025). doi: 10.1038/s41598-025-07017-2
Sujová K., Frecer V.: SARS-CoV-2 N7-methyltransferase inhibitors: Towards selective and potent antivirals. European Journal of Pharmaceutical Sciences 214, art. no. 107312 (2025). doi: 10.1016/j.ejps.2025.107312
Ďurina L., Kerti L., Litecká M., Moncoľ J., Žídeková I., Fischer R.: Zinc-Mediated Diastereoselective Acyloxyallylation of Isoxazolidine-4,5-diols. Synthesis 57(6), 1213-1222 (2025). doi: 10.1055/a-2503-2981
Chovancová M., Hubčík L., Babošová K., Klacsová M., Uhríková D.: DOPC + OTAB + DNA Complexes – Effect of Ionic Strength and Surface Charge Density on DNA Condensation. European Pharmaceutical Journal AoP,1-10 (2025). doi:10.2478/afpuc-2025-0003
Zahradníková, B., Mravíková, Z., Némethová, V., Polnišerová, P., Frecer, V., Mečiarová, M., Šebesta, R.: Utilizing N-Hydroxylamine-Based Active Esters for the Synthesis of Oseltamivir Amide Derivatives. European Journal of Organic Chemistry 28(5), (2025). doi:10.1002/ejoc.202401139
Konate, S., Allangba, K.N.P.G., Fofana, I., N'Guessan, R.K., Megnassan, E., Miertuš, S., Frecer, V.: Improved Inhibitors Targeting the Thymidylate Kinase of Multidrug-Resistant Mycobacterium tuberculosis with Favorable Pharmacokinetics. Life - Basel 15(2), art. No. 173 (2025). doi:10.3390/life15020173
Onuščáková, M., Kauerová, T., Fialová, E., Pižová, H., Garaj, V., Kemka, M., Frecer, V., Kollár, P., Bobál, P.: New potent N-hydroxycinnamamide-based histone deacetylase inhibitors suppress proliferation and trigger apoptosis in THP-1 leukaemia cells. Archiv der Pharmazie 358(4), art. no. e2400889 (2025). doi:10.1002/ardp.202400889
2024
Kerti L, Frecer V: Design of Inhibitors of SARS-CoV-2 Papain-like Protease Deriving from GRL0617: Structure – Activity Relationships. Bioorganic & Medicinal Chemistry, 113 (2024), 117909. doi: 10.1016/j.bmc.2024.117909
Pagáčová Z, Grofik M, Fazekaš T, Žufková V, Mináriková D: Screening for diabetic peripheral neuropathy at community pharmacies in Slovakia, Croatian medical journal 65 (2024) 85-92. doi: 10.3325/cmj.2024.65.85
Targošová K, Kučera M, Fazekaš T, Kilianová Z, Stankovičová T, Hrabovská A: α7 nicotinic receptors play a role in regulation of cardiac hemodynamics, Journal of Neurochemistry 168 (2024) 414-427. doi: 10.1111/jnc.15821
Čelková A, Búcsi A, Klacsová M, Fazekaš T, Martínez JC, Uhríková D: Oseltamivir phosphate interaction with model membranes, Biochimica et Biophysica Acta - Biomembranes, 1866 (2024), 184273. doi:10.1016/j.bbamem.2024.184273
Keshavarzi A, Asi Shirazi A, Korfanta R, Královič N, Klacsová M, Martínez JC, Teixeira J, Combet S, Uhríková D: Thermodynamic and Structural Study of Budesonide—Exogenous Lung Surfactant System, International Journal of Molecular Sciences 25 (2024) 2990. doi.org/10.3390/ijms25052990
Královič-Kanjaková N, Asi Shirazi A, Hubčík L, Klacsová M, Keshavarzi A, Martínez JC, Combet S, Teixeira J, Uhríková D: Polymyxin B‑Enriched Exogenous Lung Surfactant:Thermodynamics and Structure, Langmuir 40, (2024), 6847−6861. doi: 10.1021/acs.langmuir.3c03746
Kiirikki A M., Antila H S.,. Bort L S, Buslaev P, Favela-Rosales F, Ferreira T M, Fuchs P. F. J., Garcia-Fandino R, Gushchin I, Kav B, Kučerka N, Kula P, Kurki M, Kuzmin A, Lalitha A, Lolicato F, Madsen J J., Miettinen M S., Mingham C, Monticelli L, Nencini R, Nesterenko A M, Piggot T J., Piñeiro Á, Reuter N, Samantray S, Suárez-Lestón F, Talandashti R, Ollila S.O. H: Overlay databank unlocks data-driven analyses of biomolecules for all, Nature Communications, 15, Article number: 1136 (2024). doi: 10.1038/s41467-024-45189-z
Nemčovičová I, Lopušná K, Štibrániová I, Benedetti F, Berti F, Felluga F, Drioli S, Vidali M, Katrlík J, Pažitná L, Holazová A, Blahutová J, Lenhartová S, Sláviková M, Klempa B, Ondrejovič M, Chmelová D, Legerská B, Miertuš S, Klacsová M, Uhríková D, Kerti L & Frecer V: Identification and evaluation of antiviral activity of novel compounds targeting SARS-CoV-2 virus by enzymatic and antiviral assays, and computational analysis, Journal of Enzyme Inhibition and Medicinal Chemistry, 39:1 (2024), 2301772. doi: 10.1080/14756366.2024.2301772
2023
Bieri C, Esmel A, Keita M, Owono LCO, Dali B, Megnassan E, Miertuš S, Frecer V: Structure-Based Design and Pharmacophore-Based Virtual Screening of Combinatorial Library of Triclosan Analogues Active against Enoyl-Acyl Carrier Protein Reductase of Plasmodium falciparum with Favourable ADME Profiles. International Journal of Molecular Sciences 24 (2023) 6916. doi: 10.3390/ijms24086916
Mačeková Z, Fazekaš T, Krivošová M, Dragašek J, Žufková V, Klimas J, Snopková M: Identification of a Link between Suspected Metabolic Syndrome and Cognitive Impairment within Pharmaceutical Care in Adults over 75 Years of Age. Healthcare 11 (2023) 718. doi: 10.3390/healthcare11050718
Markusková L, Javorová Rihová Z, Fazekaš T, Martinkovičová A, Havrisko M, Dingová D, Soľavová M, Rábarová D, Hrabovská A: Serum butyrylcholinesterase as a marker of COVID-19 mortality: Results of the monocentric prospective observational study. Chemico-Biological Interactions 381 (2023) 110557. doi: 10.1016/j.cbi.2023.110557
Ziki E, Akonan L, Kouman KC, Dali B, Megnassan E, Kakou-Yao R, Tenon A J, Frecer V, Miertus S: Virtual design of novel coumarinyl-substituted sulfonamide inhibitors of carbonic anhydrase II as potential drugs against glaucoma. Journal of Pharmaceutical Research International 35 (2023) 10-33 (JPRI.105873). doi: 10.9734/JPRI/2023/v35i247424
2022
Klacsová M, Čelková A, Búcsi A, Martínez JC, Uhríková D: Interaction of GC376, a SARS-COV-2 MPRO inhibitor, with model lipid membranes. Colloids and Surfaces B: Biointerfaces 220 (2022) 112918. doi: 10.1016/j.colsurfb.2022.112918
Mačeková Z, Krivošová M, Fazekaš T, Snopková M, Klimas J: Short cognitive screening in elderlies as a part of advanced pharmaceutical care in Slovak community pharmacies - The pilot study KOGNIMET-SK. European Pharmaceutical Journal 69 (2022) 37-42. doi: 10.2478/afpuc-2022-0005
Čorejová A, Fazekaš T, Jánošíková D, Repiský J, Pospíšilová V, Miková M, Rauová D, Ostatníková D, Kyselovič J, Hrabovská A: Improvement of the Clinical and Psychological Profile of Patients with Autism after Methylcobalamin Syrup Administration. Nutrients 14 (2022) 2035. doi: 10.3390/nu14102035
Mačeková Z, Fazekaš T, Stanko P, Vyhnálek M, Dragašek J, Krivošová M, Křenek P, Snopková M, Klimas J: Cognitive Screening within Advanced Pharmaceutical Care in Elderly Patients with Suspected Metabolic Syndrome. International Journal of Gerontology 16 (2022) 355-360. doi: 10.6890/IJGE.202210_16(4).0008
Kurakin S, Ivankov O, Skoi V, Kuklin A, Uhríková D, Kučerka N: Cations do not alter the membrane structure of POPC – A lipid with an intermediate area. Frontiers in Molecular Biosciences 9 (2022) 926591. doi: 10.3389/fmolb.2022.926591
Claro B, González-Freire E, Granja JR, Garcia-Fandiño, R, Gallová J, Uhríková D, Fedorov A, Coutinho A, Bastos M: Partition of antimicrobial D-L-α-cyclic peptides into bacterial model membranes. Biochimica et Biophysica Acta - Biomembranes 1864 (2022) 183729. doi: 10.1016/j.bbamem.2021.183729
2021
Klacsová M, Bóta A, Westh P, Funari SS, Uhríková D, Balgavý P: Thermodynamic and structural study of DMPC-alkanol systems. Physical Chemistry Chemical Physics 23 (2021) 8598. doi: 10.1039/D0CP04991C
Královič N, Hubčík L, Búcsi A, Klacsová M, Combet S, Teixeira J, Martínez JC, Uhríková D: Calcium mediated DNA binding in non-lamellar structures formed by DOPG/glycerol monooleate. Chemistry and Physics of Lipids 239 (2021) 105118. doi: 10.1016/j.chemphyslip.2021.105118
Kučerka N, Ermakova E, Dushanov E, Kholmurodov K, Kurakin S, Želinská K, Uhríková D: Cation-zwitterionic lipid interactions are affected by the lateral area per lipid. Langmuir 37 (2021) 278. doi: 10.1021/acs.langmuir.0c02876
Vitková Z, Tárník M, Pavlovičová J, Vitko A, Oremusová J, Murgaš J, Babinec A: From Static to Dynamic Modeling of Surfactants Micellization. Tenside, Surfactants, Detergents 58 (2021) 4. doi: 10.1515/tsd-2020-2296
Uhríková D: Phospholipid bilayers in model membranes and drug delivery systems: from physics to pharmacy. European Pharmaceutical Journal 68 (2021) 66. doi: 10.2478/afpuc-2021-0008
Želinská K, Gallová J: Study of the solubilisation process of bacterial model membranes induced by DDAO. European Pharmaceutical Journal 68 (2021) 17. doi: 10.2478/afpuc-2020-0019
Fofana I, Dali B, Mansilla-Koblavib F, Megnassan E, Frecer V, Miertus S: Structure-based design of tetrahydroisoquinoline-based hydroxamic acid derivatives inhibiting human histone deacetylase 8. Journal of Computational Chemistry & Molecular Modeling 5 (2021) 504-538. doi: 10.25177/JCCMM.5.1.RA.10708
2020
Braccini S, Pecorini G, Chiellini F, Bakoš D, Miertuš S, Frecer V: Adhesion of fibroblast cells on thin films representing surfaces ofpolymeric scaffolds of human urethra rationalized by molecular models of integrin binding: cell adhesion on polymeric scaffolds for regenerative medicine. Journal of Biotechnology 324 (2020) 233. doi: 10.1016/j.jbiotec.2020.11.001
Džubák P, Gurská S, Bogdanová K, Uhríková D, Kanjaková N, Combet S, Klunda T, Kolář M, Hajdúch M, Poláková M: Antimicrobial and cytotoxic activity of (thio)alkyl hexopyranosides, nonionic glycolipid mimetics. Carbohydrate Research 488 (2020) 107905. doi: 10.1016/j.carres.2019.107905
Frecer V, Miertuš S: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease. RSC Advances 10 (2020) 40244. doi: 10.1039/D0RA08304F
Lipničanová S, Chmelová D, Ondrejovič M, Frecer V, Miertuš S: Diversity of sialidases found in the human body - A review. International Journal of Biological Macromolecules 148 (2020) 857. doi: 10.1016/j.ijbiomac.2020.01.123
Puchoň E, Göböová M, Vaňo I, Fazekaš T, Javorová-Rihová Z, Kuželová M: Medication-related factors associated with proton pump inhibitor prescription beyond official guidelines in older adults. European Geriatric Medicine 11 (2020) 1051. doi: 10.1007/s41999-020-00380-5
Vaneková Z, Hubčík L, TocaHerrera JL, Furtmüller PG, Mučaji P, Nagy M: Analysis of binding interactions oframipril and quercetin on human serum albumin: A novel method in affinity evaluation. Molecules 25 (2020) 547. doi: 10.3390/molecules25030547
Vitková Z, Oremusová J, Vitko A, Ivánková O, Tárník M, Murgaš J, Oremus V, Miklovičová Eva: Modeling of association properties ofcetylpyridinium halides (Cl, Br) and their influence on liberation and rheological and pH balances of hydrogels with ibuprofen. Tenside Surfactants Detergents 57 (2020) 442. doi: 10.3139/113.110713
Vitková Z, Tárník M, Miklovičová E, Murgaš J, Oremusová J, Vitko A: System-based approach to prediction of surfactants' influences on pharmaco-kinetics and pharmacodynamics. Tenside Surfactants Detergents 57 (2020) 33. doi: 10.3139/113.110661
Želinská K, Gallová J, Huláková S, Uhríková D, Ivankov O: Solubilisation of model membrane by DDAO surfactant - partitioning, permeabilisation and liposome-micelle transition. General Physiology and Biophysics 39 (2020) 107. doi: 10.4149/gpb_2019056
Murugova T, Ivankov O, Ermakova E, Kondela T, Hrubovčák P, Skoi V, Kuklin A, Kučerka N: Structural changes introduced by cholesterol and melatonin to the model membranes mimicking preclinical conformational diseases. General Physiology and Biophysics 39 (2020) 135. doi: 10.4149/gpb_2019054
Vitková Z, Pavlovičová J, Murgaš J, Vitko A, Oremusová J, Tárník M: Farmakokinetické modelovanie I.: Kompartmentové modelovanie. Praktické lekárnictvo 10 (2020) 32.
Mačeková Z, Fazekaš T, Klimas J: Úloha farmaceuta pri hodnotení kognitívneho stavu rizikových pacientov v lekárenskej praxi. Pokroky vo farmakológii v Slovenskej republike XV. Bratislava: Farmaceutická fakulta UK (2020) 88. ISBN 978-80-223-5017-4
Puchoň E, Fazekaš T, Javorová-Rihová Z, Göböová M, Kuželová M: Analýza potenciálne nevhodnej preskripcie inhibítorov protónovej pumpy u starších pacientov. Pokroky vo farmakológii v Slovenskej republike XV. Bratislava: Farmaceutická fakulta UK (2020) 81. ISBN 978-80-223-5017-4
2019
Kučerka N, Uhríková D: Biophysical perspectives of lipid membranes through the optics of neutron and X-ray scattering. Characterization of Biological Membranes: Structure and Dynamics. Berlin: De Gruyter (2019) 1. ISBN 9783110544657
Vitková Z, Oremusová J, Vitko A, Matušová D: Fyzikálno technologické princípy emulzií. Bratislava: Felia (2019). ISBN 978-80-89824-10-6
Allangba KNPG, Keita M, N'Guessan R, Megnassan E, Frecer V, Miertuš S: Virtual design of novel Plasmodium falciparum cysteine protease falcipain-2 hybrid lactone-chalcone and isatin-chalcone inhibitors probing the S2 active site pocket. Journal of Enzyme Inhibition and Medicinal Chemistry 34 (2019) 547. doi: 10.1080/14756366.2018.1564288
Colombo L, Abeshi A, Maltese PE, Frecer V, Miertuš J, Cerra D, Bertelli M, Rossetti L: Oguchi type I caused by a homozygous missense variation in the SAG gene. European Journal of Medical Genetics 62 (2019) 103548. doi: 10.1016/j.ejmg.2018.09.015
Frecer V, Iarossi G, Salvetti AP, Maltese PE, Delledonne G, Oldani M, Staurenghi G, Falsini B, Minnella AM, Ziccardi L, Magli A, Colombo L, D`Esposito F, Miertuš J, Viola F, Attanasio M, Maggio E, Bertelli M: Pathogenicity of new BEST1 variants identified in Italian patients with best vitelliform macular dystrophy assessed by computational structural biology. Journal of Translational Medicine 17 (2019) 330. doi: 10.1186/s12967-019-2080-3
Hrubovčák P, Kondela T, Ermakova E, Kučerka N: Application of small‑angle neutron diffraction to the localization of general anesthetics in model membranes. European Biophysics Journal 48 (2019) 447. doi: 10.1007/s00249-019-01370-7
Kollár J, Morelli A, Chiellini F, Miertuš S, Bakoš D, Frecer V: Epithelial cell adhesion on films mimicking surface of polymeric scaffolds of artificial urethra compared to molecular modeling of integrin binding. Journal of Bioactive and Compatible Polymers 34 (2019) 280. doi: 10.1177/0883911519843309
Kouman KCh, Keita M, N`Guessan RK, Owono Owono LC, Megnassan E, Frecer V, Miertuš S: Structure-based design and in silico screening of virtual combinatorial library of benzamides inhibiting 2-trans enoyl-acyl carrier protein reductase of mycobacterium tuberculosis with favorable predicted pharmacokinetic profiles. International Journal of Molecular Sciences 20 (2019) 4730. doi: 10.3390/ijms20194730
Kučerka N, Hrubovčák P, Dushanov E, Kondela T, Kholmurodov KT, Gallová J, Balgavý P: Location of the general anesthetic n-decane in model membranes. Journal of Molecular Liquids 276 (2019) 624. doi: 10.1016/j.molliq.2018.12.039
Liskayová G, Hubčík L, Búcsi A, Fazekaš T, Martínez JC, Devínsky F, Pisárčik M, Hanulová M, Ritz S, Uhríková D: pH-sensitive N,N-dimethylalkane-1-amine N-oxides in DNA delivery: From structure to transfection efficiency. Langmuir 35 (2019) 13382. doi: 10.1021/acs.langmuir.9b02353
Oremusová J, Vitková Z, Vitko A, Tárník M, Ivánková O, Murgaš J, Miklovičová E, Krchňák D: Effect of molecular composition of head group and temperature on micellar properties of ionic surfactants with C12 alkyl chain. Molecules 24 (2019) 651. doi: 10.3390/molecules24030651
Pisárčik M, Pupák M, Lukáč M, Devínsky F, Hubčík L, Bukovský M, Horváth B: The synthesis, self-assembled structures, and microbicidal activity of cationic gemini surfactants with branched tridecyl chains. Molecules 24 (2019) 4380. doi: 10.3390/molecules24234380
Vaneková Z, Hubčík L, TocaHerrera JL, Furtmüller PG, Valentová J, Mučaji P, Nagy M: Study of interactions between amlodipine and quercetin on human serum albumin: Spectroscopic and modeling approaches. Molecules 24 (2019) 487. doi: 10.3390/molecules24030487
Mináriková D, Dúbravová E, Fazekaš T, Harag T: Bolesti chrbta, pracovné podmienky a pracovná záťaž u zamestnancov lekární. Súčasná klinická prax 1 (2019) 14.
Mináriková D, Fazekaš T, Minárik P, Jurišová E: Assessment of patient counselling on the common cold treatment at Slovak community pharmacies using mystery shopping. Saudi Pharmaceutical Journal 27 (2019) 574. doi: 10.1016/j.jsps.2019.02.005
Kučerka N, Gallová J, Uhríková D: The membrane structure and function affected by water. Chemistry and Physics of Lipids 221 (2019) 140. doi: 10.1016/j.chemphyslip.2019.04.002
Mináriková D, Fazekaš T, Stanko P: Mystery shopping a vzdelávanie študentov farmácie pri dispenzácii a poradenstve o OTC lieku. Klinická farmakologie a farmacie 33 (2019) 4. doi: 10.36290/far.2019.008
Göböová M, Vaňo I, Kissová V, Fazekaš T, Kuželová M: Is gentamicin administered to individual patients in optimal doses already at the beginning of therapy? European Pharmaceutical Journal 66 (2019) 11. doi: 10.2478/afpuc-2019-0002